Factors associated with treatment failure of direct‐acting antivirals for chronic hepatitis C: A real‐world nationwide hepatitis C virus registry programme in Taiwan

Author:

Chen Chi‐Yi1,Huang Chung‐Feng23ORCID,Cheng Pin‐Nan4,Tseng Kuo‐Chih56ORCID,Lo Ching‐Chu7,Kuo Hsing‐Tao8ORCID,Huang Yi‐Hsiang910ORCID,Tai Chi‐Ming1112,Peng Cheng‐Yuan13ORCID,Bair Ming‐Jong1415,Chen Chien‐Hung16ORCID,Yeh Ming‐Lun317ORCID,Lin Chih‐Lang18,Lin Chun‐Yen1920ORCID,Lee Pei‐Lun21,Chong Lee‐Won2223,Hung Chao‐Hung1624,Huang Jee‐Fu325ORCID,Yang Chi‐Chieh26,Hu Jui‐Ting27,Lin Chih‐Wen1228ORCID,Chen Chun‐Ting2930,Wang Chia‐Chi31,Su Wei‐Wen32,Hsieh Tsai‐Yuan30ORCID,Lin Chih‐Lin33,Tsai Wei‐Lun34,Lee Tzong‐Hsi35,Chen Guei‐Ying36,Wang Szu‐Jen37,Chang Chun‐Chao3839,Mo Lein‐Ray40,Yang Sheng‐Shun41,Wu Wen‐Chih42,Huang Chia‐Sheng43,Hsiung Chou‐Kwok44,Kao Chien‐Neng45ORCID,Tsai Pei‐Chien2,Liu Chen‐Hua46ORCID,Lee Mei‐Hsuan47ORCID,Liu Chun‐Jen46,Dai Chia‐Yen23ORCID,Kao Jia‐Horng46ORCID,Chuang Wan‐Long23,Lin Han‐Chieh910ORCID,Yu Ming‐Lung23ORCID

Affiliation:

1. Division of Gastroenterology and Hepatology Department of Medicine Ditmanson Medical Foundation Chiayi Christian Hospital Chiayi Taiwan

2. Hepatobiliary Division Department of Internal Medicine and Hepatitis Center Kaohsiung Medical University HospitalKaohsiung Medical University Kaohsiung Taiwan

3. School of Medicine and Hepatitis Research Center College of Medicine, and Center for Cancer Research and Center for Liquid Biopsy and Cohort Research Kaohsiung Medical University Kaohsiung Taiwan

4. Division of Gastroenterology and Hepatology Department of Internal Medicine College of Medicine National Cheng Kung University HospitalNational Cheng Kung University Tainan Taiwan

5. Department of Internal Medicine Dalin Tzu Chi HospitalBuddhist Tzu Chi Medical Foundation Chiayi Taiwan

6. School of Medicine Tzuchi University Hualien Taiwan

7. Division of Gastroenterology Department of Internal Medicine St. Martin De Porres Hospital Chiayi Taiwan

8. Division of Gastroenterology and Hepatology Department of Internal Medicine Chi Mei Medical Center Tainan Taiwan

9. Division of Gastroenterology and Hepatology Department of Medicine Taipei Veterans General Hospital

10. Institute of Clinical Medicine School of Medicine National Yang‐Ming University Taipei Taiwan

11. Department of Internal Medicine E‐Da Hospital Kaohsiung Taiwan

12. School of Medicine College of Medicine I‐Shou University Kaohsiung Taiwan

13. Center for Digestive Medicine Department of Internal Medicine School of Medicine China Medical University HospitalChina Medical University Taichung Taiwan

14. Division of Gastroenterology Department of Internal Medicine Taitung Mackay Memorial Hospital Taitung Taiwan

15. Mackay Medical College New Taipei City Taiwan

16. Division of Hepato‐Gastroenterology Department of Internal Medicine Kaohsiung Chang Gung Memorial HospitalCollege of MedicineChang Gung University Taoyuan Taiwan

17. Department of Internal Medicine Kaohsiung Municipal Siaogang HospitalKaohsiung Medical University HospitalKaohsiung Medical University Kaohsiung Taiwan

18. Department of Gastroenterology and Hepatology Keelung Chang Gung Memorial Hospital Keelung Taiwan

19. Department of Gastroenterology and Hepatology Chang Gung Memorial HospitalLinkou Branch Taoyuan Taiwan

20. Graduate Institute of Biomedical Science College of Medicine Chang Gung University Taoyuan Taiwan

21. Liouying Division of Gastroenterology and Hepatology Department of Internal medicine Chi Mei Medical Center Tainan Taiwan

22. Division of Hepatology and Gastroenterology Department of Internal Medicine Shin Kong Wu Ho‐Su Memorial Hospital Taipei Taiwan

23. School of Medicine Fu‐Jen Catholic University New Taipei City Taiwan

24. Division of Hepatogastroenterology Department of Internal Medicine ChiaYi Chang Gung Memorial Hospital Puzi Taiwan

25. Department of Internal Medicine Kaohsiung Municipal Ta‐Tung HospitalKaohsiung Medical University HospitalKaohsiung Medical University Kaohsiung Taiwan

26. Department of Gastroenterology Division of Internal Medicine Show Chwan Memorial Hospital Changhua Taiwan

27. Liver Center Cathay General Hospital Taipei Taiwan

28. Division of Gastroenterology and Hepatology E‐Da Dachang Hospital Kaohsiung Taiwan

29. Division of Gastroenterology Department of Internal Medicine Tri‐Service General Hospital Penghu Branch National Defense Medical Center Taipei Taiwan

30. Division of Gastroenterology Department of Internal Medicine Tri‐Service General Hospital National Defense Medical Center Taipei Taiwan

31. School of Medicine Taipei Tzu Chi HospitalBuddhist Tzu Chi Medical FoundationTzu Chi University Hualien Taiwan

32. Department of Gastroenterology and Hepatology Changhua Christian Hospital Changhua Taiwan

33. Department of Gastroenterology Renai branch Taipei City Hospital Taipei Taiwan

34. Division of Gastroenterology and Hepatology Department of Internal Medicine Kaohsiung Veterans General Hospital Kaohsiung Taiwan

35. Division of Gastroenterology and HepatologyFar Eastern Memorial Hospital New Taipei City Taiwan

36. Penghu HospitalMinistry of Health and Welfare Taipei Taiwan

37. Division of Gastroenterology Department of Internal Medicine Yuan’s General Hospital Kaohsiung Taiwan

38. Division of Gastroenterology and Hepatology Department of Internal Medicine Taipei Medical University Hospital Taipei Taiwan

39. Division of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine College of Medicine Taipei Medical University Taipei Taiwan

40. Division of Gastroenterology Tainan Municipal Hospital Tainan Taiwan

41. Division of Gastroenterology and Hepatology Department of Internal Medicine Taichung Veterans General Hospital Taichung Taiwan

42. Wu Wen‐Chih Clinic Kaohsiung Taiwan

43. Yang Ming Hospital Chiayi Taiwan

44. Chou Kwok Hsiung Clinic Penghu Taiwan

45. National Taiwan University Hospital Hsin‐Chu Branch Hsinchu Taiwan

46. Hepatitis Research Center and Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan

47. Institute of Clinical Medicine National Yang Ming Chiao Tung University Taipei Taiwan

Publisher

Wiley

Subject

Hepatology

Reference44 articles.

1. Global prevalence and genotype distribution of hepatitis C virus infection in a modelling study;The Polaris Observatory HCV Collaborators;The lancet Gastroenterology & hepatology,2015

2. EASL recommendations on treatment of hepatitis C: Final update of the series☆

3. HCV Guidance: Recommendations for Testing Managing and Treating Hepatitis C.http://www.hcvguidelines.org/. Accessed on Dec 15 2019

4. Huge Gap Between Clinical Efficacy and Community Effectiveness in the Treatment of Chronic Hepatitis C

5. Viral Hepatitis Infections in Southern Taiwan: A Multicenter Community-based Study

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