Fatty acid starvation activates RelA by depleting lysine precursor pyruvate
Author:
Affiliation:
1. Centre of Excellence for Bacterial Stress Response and Persistence, Department of Biology University of Copenhagen Copenhagen Denmark
2. Department of Molecular Biology Umeå University Umeå901 87Sweden
Funder
Danmarks Grundforskningsfond
Novo Nordisk Fonden
Publisher
Wiley
Subject
Molecular Biology,Microbiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/mmi.14366
Reference53 articles.
1. The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis
2. The RelA/SpoT Homolog (RSH) Superfamily: Distribution and Functional Evolution of ppGpp Synthetases and Hydrolases across the Tree of Life
3. Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection
4. Acyl carrier protein/SpoT interaction, the switch linking SpoT-dependent stress response to fatty acid metabolism
5. Bacteria Possessing Two RelA/SpoT-Like Proteins Have Evolved a Specific Stringent Response Involving the Acyl Carrier Protein-SpoT Interaction
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