Evaluation of the potential for pharmacokinetic interaction between tirabrutinib and levonorgestrel/ethinyl estradiol in healthy female volunteers

Author:

Cherala Ganesh1,Nelson Cara1,Guo Ying1,Mathur Anubhav1,Tarnowski Thomas1ORCID,Othman Ahmed A.1ORCID

Affiliation:

1. Gilead Sciences, Inc. Foster City California USA

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Reference19 articles.

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2. ONO‐4059 ‐ a potent and selective reversible Bruton's tyrosine kinase (BTK) inhibitor: single agent, twice daily (BD) dosing and dosing with food results in sustained, high trough levels of ONO‐4059, translating into 100% tumour remission in a TMD‐8 xenograft model;Toshio Y;Blood,2014

3. Tirabrutinib: First Approval

4. Pharmaceuticals and Medical Devices Agency.https://www.pmda.go.jp/files/000237315.pdf. Accessed October 8 2021.

5. National Survey of Family Growth 2015–2017.The National Center for Health Statistics Centers for Disease Control and Prevention.https://www.cdc.gov/nchs/nsfg/nsfg_2015_2017_puf.htm. Accessed October 8 2021.

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