Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav 1.7 mutation I234T-Reference-Cited by-同舟云学术

Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav 1.7 mutation I234T

Published:2017-07-30 Issue:12 Volume:175 Page:2261-2271
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:British Journal of Pharmacology

Author:

Yang Yang¹²³,Adi Talia¹²³,Effraim Philip R¹²³⁴,Chen Lubin¹²³,Dib-Hajj Sulayman D¹²³,Waxman Stephen G¹²³^ORCID

Affiliation:

1. Department of Neurology; Yale University School of Medicine; New Haven CT USA

2. Center for Neuroscience and Regeneration Research; Yale University School of Medicine; New Haven CT USA

3. Rehabilitation Research Center; VA Connecticut Healthcare System; West Haven CT USA

4. Department of Anesthesiology; Yale University School of Medicine; New Haven CT USA

Funder

CT innovations

U.S. Department of Veterans Affairs

Kenneth Rainin Foundation

Regenerative Medicine Research Fund (RMRF) of CT Innovations

Medical Research Service and Rehabilitation Research Service, Department of Veterans Affairs

Publisher

Wiley

Subject

Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.13935/fullpdf

Reference48 articles.

1. A new Nav1.7 sodium channel mutation I234T in a child with severe pain;Ahn;Eur J Pain,2010

2. The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels;Alexander;Br J Pharmacol,2015a

3. The Concise Guide to PHARMACOLOGY 2015/16: Overview;Alexander;Br J Pharmacol,2015b

4. A case for “StopGo”: reprogramming translation to augment codon meaning of GGN by promoting unconventional termination (Stop) after addition of glycine and then allowing continued translation (Go);Atkins;RNA,2007

5. Liquid chromatography-electrospray mass spectrometry determination of carbamazepine, oxcarbazepine and eight of their metabolites in human plasma;Breton;J Chromatogr B Analyt Technol Biomed Life Sci,2005

Cited by 26 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Erythromelalgia caused by the missense mutation p.Arg220Pro in an alternatively spliced exon of SCN9A (NaV1.7);Human Molecular Genetics;2023-09-18

2. Nav1.7 gain-of-function mutation I228M triggers age-dependent nociceptive insensitivity and C-LTMR dysregulation;Experimental Neurology;2023-06

3. Gene therapy for chronic pain: emerging opportunities in target-rich peripheral nociceptors;Nature Reviews Neuroscience;2023-01-19

4. Erythromelalgia: A Review of Medical Management Options and Our Approach to Management;Mayo Clinic Proceedings;2023-01

5. Inhibition of intracellular proton-sensitive Ca2+-permeable TRPV3 channels protects against ischemic brain injury;Acta Pharmaceutica Sinica B;2022-05