Off‐target inhibition of NGLY1 by the polycaspase inhibitor Z‐VAD‐fmk induces cellular autophagy-Reference-Cited by-同舟云学术

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Off‐target inhibition of NGLY1 by the polycaspase inhibitor Z‐VAD‐fmk induces cellular autophagy

Published:2022-01-18 Issue:11 Volume:289 Page:3115-3131
ISSN:1742-464X
Container-title:The FEBS Journal
language:en
Short-container-title:The FEBS Journal

Author:

Needs Sarah H.¹²,Bootman Martin D.¹,Grotzke Jeff E.³,Kramer Holger B.⁴⁵,Allman Sarah A.¹²⁶^ORCID

Affiliation:

1. School of Life, Health and Chemical Sciences The Open University Milton Keynes UK

2. Reading School of Pharmacy University of Reading UK

3. Yale University School of Medicine New Haven CT USA

4. Department of Physiology, Anatomy and Genetics University of Oxford UK

5. MRC London Institute of Medical Sciences UK

6. Leicester School of Pharmacy De Montfort University Leicester UK

Funder

Royal Society

Engineering and Physical Sciences Research Council

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/febs.16345

Reference53 articles.

1. Non-specific effects of methyl ketone peptide inhibitors of caspases

2. Calpain activation is upstream of caspases in radiation-induced apoptosis

3. Using a Small Molecule Inhibitor of Peptide: N-Glycanase to Probe Its Role in Glycoprotein Turnover

4. Antiviral activity of caspase inhibitors: effect on picornaviral 2A proteinase

5. Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors

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2. A Natural Compound Containing a Disaccharide Structure of Glucose and Rhamnose Identified as Potential N-Glycanase 1 (NGLY1) Inhibitors;Molecules;2023-11-24

3. Nano-selenium protects grass carp hepatocytes against 4-tert-butylphenol-induced mitochondrial apoptosis and necroptosis via suppressing ROS-PARP1 axis;Fish & Shellfish Immunology;2023-04

4. Generation and characterization of NGLY1 patient-derived midbrain organoids;Frontiers in Cell and Developmental Biology;2023-02-16

5. Sugar coating autophagy: exploring the links between the inhibition of NGLY1 (N-glycanase 1) and autophagy induction;Autophagy Reports;2023-01-16

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