Structure‐based engineering of a short‐chain cis ‐prenyltransferase to biosynthesize nonnatural all‐ cis ‐polyisoprenoids: molecular mechanisms for primer substrate recognition and ultimate product chain‐length determination

Author:

Kutsukawa Ryo1,Imaizumi Riki2,Suenaga‐Hiromori Miki1,Takeshita Kohei3,Sakai Naoki3,Misawa Shuto2,Yamamoto Masaki3,Yamaguchi Haruhiko4,Miyagi‐Inoue Yukino4,Waki Toshiyuki1,Kataoka Kunishige2,Nakayama Toru1,Yamashita Satoshi2,Takahashi Seiji1ORCID

Affiliation:

1. Graduate School of Engineering Tohoku University Sendai Japan

2. Department of Material Chemistry Graduate School of Natural Science and Technology Kanazawa University Japan

3. RIKEN SPring‐8 Center Sayo‐gun Japan

4. Sumitomo Rubber Industries, Ltd Kobe Japan

Funder

Japan Agency for Medical Research and Development

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

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