CTLA-4Ig (abatacept) balances bone anabolic effects of T cells and Wnt-10b with antianabolic effects of osteoblastic sclerostin

Author:

Roser-Page Susanne1,Vikulina Tatyana12,Weiss Daiana2,Habib Mark M.12,Beck George R.123,Pacifici Roberto24,Lane Timothy F.5,Weitzmann M. Neale123

Affiliation:

1. Atlanta VA Medical Center; Decatur Georgia

2. Division of Endocrinology and Metabolism and Lipids; Department of Medicine, Emory University School of Medicine; Atlanta Georgia

3. Emory Winship Cancer Institute; Emory University; Atlanta Georgia

4. Immunology and Molecular Pathogenesis Program; Emory University; Atlanta Georgia

5. Departments of Obstetrics and Gynecology and Biological Chemistry, and Orthopedic Hospital Research Center; University of California Los Angeles; Los Angeles California

Funder

Biomedical Laboratory Research and Development, VA Office of Research and Development

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Institute on Aging

BLRD

National Institutes of Health

Publisher

Wiley

Subject

History and Philosophy of Science,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

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