Down-regulation of natural resistance-associated macrophage protein-1 (Nramp1) is associated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)/1-methyl-4-phenylpyridinium (MPP+ )-induced α-synuclein accumulation and neurotoxicity

Author:

Wu K.-C.1,Liou H.-H.2,Lee C.-Y.1,Lin C.-J.1ORCID

Affiliation:

1. School of Pharmacy; National Taiwan University; Taipei Taiwan

2. Department of Neurology; National Taiwan University Hospital; Taipei Taiwan

Funder

Ministry of Science and Technology, Taiwan

Publisher

Wiley

Subject

Physiology (medical),Neurology (clinical),Neurology,Histology,Pathology and Forensic Medicine

Reference52 articles.

1. Alpha-synuclein and neurodegenerative diseases;Goedert;Nat Rev Neurosci,2001

2. The role of alpha-synuclein in Parkinson′s disease: insight from animal models;Maries;Nat Rev Neurosci,2003

3. α-Synuclein oligomers and clinical implications for Parkinson's disease;Kalia;Ann Neurol,2013

4. Increased expression of alpha-synuclein reduced neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis;Nemani;Neuron,2010

5. Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation;Chen;J Clin Invest,2009

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