Does ponatinib cross the blood-brain barrier?

Author:

Abid Muhammad B.1,De Mel Sanjay1

Affiliation:

1. Department of Haematology/Oncology; National University Cancer Institute Singapore (NCIS); Singapore

Publisher

Wiley

Subject

Hematology

Reference6 articles.

1. A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias;Cortes;New England Journal of Medicine,2013

2. Dasatinib as first-line treatment for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia;Foà;Blood,2011

3. Isolated central nervous system relapse in two patients with BCR-ABL-positive acute leukemia while receiving a next-generation tyrosine kinase inhibitor;Gaur;In Vivo,2014

4. Central nervous system prophylaxis in adults with acute lymphoblastic leukemia: current and emerging therapies;Jabbour;Cancer,2010

5. Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia;Porkka;Blood,2008

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