Impact of diabetes on weight loss outcomes after bariatric surgery: Experience from 5‐year follow‐up of Michigan Bariatric Surgery Cohort

Author:

Luo Yingying12,Haddad Raad A.1,Ontan Mehmet Selman1ORCID,Eldin Abdel Wahab Jalal1,Abu‐Rumaileh Mohammed3ORCID,Yosef Matheos4,Khalatbari Shokoufeh4,Varban Oliver5,Kraftson Andrew1,Esfandiari Nazanene H.1,Oral Elif A.1ORCID

Affiliation:

1. Division of Metabolism, Endocrinology & Diabetes (MEND), Department of Internal Medicine, Michigan Medicine University of Michigan Ann Arbor Michigan USA

2. Department of Endocrinology and Metabolism Peking University People's Hospital Beijing China

3. Department of Internal Medicine University of Toledo Toledo Ohio United States

4. Michigan Institute for Clinical and Health Research, Biostatistics Core University of Michigan Ann Arbor Michigan USA

5. Department of General Surgery University of Michigan Ann Arbor Michigan USA

Abstract

AbstractObjectiveFor patients with obesity and diabetes, bariatric surgery can lead to the remission of both diseases. However, the possible impact of diabetes on the magnitude of weight loss outcomes after bariatric surgery has not been precisely quantified.Research Design and MethodsData from Michigan Bariatric Surgery Cohort (MI‐BASiC) was extracted to examine the effect of baseline diabetes on weight loss outcomes. Consecutive patients older than 18 years of age undergoing gastric bypass (GB) or sleeve gastrectomy (SG) for obesity at University of Michigan between January 2008 and November 2013 were included. Repeated measures analysis was used to determine if diabetes was a predictor of weight loss outcomes over 5 years postsurgery.ResultsOut of the 714 included patients, 380 patients underwent GB [mean BMI 47.3 ± 0.4 kg/m2, diabetes 149 (39.2%)] and 334 SG [mean BMI 49.9 ± 0.5 kg/m2, diabetes 108 (32.3%)]. Multivariable repeated measures analysis showed, after adjusting for covariates, that individuals with diabetes had a significantly lower percentage of total (p = .0023) and excess weight loss (p = .0212) compared to individuals without diabetes.ConclusionsOur data demonstrate that patients with diabetes undergoing bariatric surgery would experience less weight loss than patients without diabetes.

Publisher

Wiley

Subject

Endocrinology, Diabetes and Metabolism,Endocrinology

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