Short‐term safety and effectiveness of sugammadex for surgical patients with end‐stage renal disease: a two‐centre retrospective study
Author:
Affiliation:
1. Department of Anesthesiology and Peri‐operative Medicine University of Pittsburgh Medical Center Pittsburgh PA USA
2. Department of Anesthesiology and Critical Care Medicine Memorial Sloan Kettering Cancer Center New York NY USA
Funder
Memorial Sloan-Kettering Cancer Center
Publisher
Wiley
Subject
Anesthesiology and Pain Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/anae.14914
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2. A Novel Concept of Reversing Neuromuscular Block: Chemical Encapsulation of Rocuronium Bromide by a Cyclodextrin-Based Synthetic Host The discovery of Org 25969 is the result of teamwork with contributions from a number of scientists both inside Organon and outside the company. We would like in particular to acknowledge the following scientists for their invaluable contributions: E. Hutchinson, D. Stevenson, R. Roy, and J. Pick for scaling-up the synthesis; F. Hope, S. Miller, and R. Mason for various in vitro and in vivo pharmacological testing; R. Watson, B. Montgomery, P. Desmond, and A. Osprey for all their analytical effort; and R. McGuire and J. Mestres for graphical presentation of the X-ray crystal structure of the Org 25969–rocuronium complex (Figure 3). We would also like to thank Prof. A. Cooper of Glasgow University who has critically reproduced our calorimetry data of Org 25969–rocuronium complexation (Figure 2).
3. Reversal of Meeting Abstracts and Simultaneous Increase in Plasma Rocuronium Concentration after the Intravenous Infusion of the Novel Reversal Agent Org 25969
4. First Human Exposure of Org 25969, a Novel Agent to Reverse the Action of Rocuronium Bromide
5. Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults;Hristovska AM;Cochrane Database of Systematic Reviews,2017
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