Intracellular pharmacokinetics of gemcitabine, its deaminated metabolite 2′,2′-difluorodeoxyuridine and their nucleotides-Reference-Cited by-同舟云学术

Intracellular pharmacokinetics of gemcitabine, its deaminated metabolite 2′,2′-difluorodeoxyuridine and their nucleotides

Published:2018-04-16 Issue:6 Volume:84 Page:1279-1289
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Derissen Ellen J. B.¹²^ORCID,Huitema Alwin D. R.¹³,Rosing Hilde¹,Schellens Jan H. M.⁴⁵,Beijnen Jos H.¹⁵

Affiliation:

1. Department of Pharmacy & Pharmacology; Antoni van Leeuwenhoek Hospital - The Netherlands Cancer Institute and MC Slotervaart; Louwesweg 6, 1066 EC Amsterdam The Netherlands

2. Department of Clinical Pharmacology and Pharmacy; VU University Medical Center; De Boelelaan 1117 1081 HV Amsterdam The Netherlands

3. Department of Clinical Pharmacy; University Medical Center Utrecht; Heidelberglaan 100 3584 CX Utrecht The Netherlands

4. Department of Clinical Pharmacology; The Netherlands Cancer Institute; Plesmanlaan 121 1066 CX Amsterdam The Netherlands

5. Science Faculty, Utrecht Institute for Pharmaceutical Sciences (UIPS), Division of Pharmaco-epidemiology & Clinical Pharmacology; Utrecht University; P.O. Box 80082 3508 TB Utrecht The Netherlands

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.13557/fullpdf

Reference47 articles.

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3. Clinical pharmacology and pharmacogenetics of gemcitabine;Wong;Drug Metab Rev,2009

4. Excision of 2′,2′-difluorodeoxycytidine (gemcitabine) monophosphate residues from DNA;Gandhi;Cancer Res,1996

5. Action of 2′,2′-difluorodeoxycytidine on DNA synthesis;Huang;Cancer Res,1991

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