Long‐term safety and efficacy of ravulizumab in patients with paroxysmal nocturnal hemoglobinuria: 2‐year results from two pivotal phase 3 studies

Author:

Kulasekararaj Austin G.1ORCID,Griffin Morag2,Langemeijer Saskia3,Usuki Kensuke4,Kulagin Alexander5ORCID,Ogawa Masayo6,Yu Ji6,Mujeebuddin Arshad6,Nishimura Jun‐ichi7,Lee Jong Wook8,Peffault de Latour Régis9,Latypova Aigul,Barcellini Wilma,Barraco Fiorenza,Beam Donald,Bettelheim Peter,Borisenkova Elena,Brodsky Andres,Carnley Benedict,Cermak Jaroslav,Chen Tsai‐Yun,Chew Lee Ping,Chew Teng Keat,Choi Chul Won,Choi Yunsuk,Chung Joo Seop,De Guibert Sophie,Devos Timothy,Dunaev Yuri,Dwilewicz‐Trojaczek Jadwiga,Edahiro Yoko,Elykomov Iliya,Engelberger Maria Ines,Pomponi Fabrizio,Fuereder Wolfgang,Fujii Nobuharu,Fujiwara Shinichiro,Galieni Piero,Gaya Valls Anna,Girault Stéphane,Gomez Almaguer David,Gonzalez Fernandez F. Ataulfo,Gritsaev Sergey,Gunduz Eren,Hantaweepant Chattree,Harada Hiroshi,Höglund Martin,Huang Wei‐Han,Husin Azlan,Ikezoe Takayuki,Ishiyama Ken,Ito Yoshikazu,Jang Jun Ho,Jo Deog‐Yeon,Kang Ka‐Won,Kennedy James,Kim Hyo Jung,Kim Jeong‐A,Kim Jin Seok,Kimura Fumihiko,Kobune Masayoshi,Kosugi Hiroshi,Kulagin Alexander,Kulasekararaj Austin,Lai Kuan‐Ming,Larratt Loree,Lee Gyeong‐Won,Lee Jae Hoon,Lee Je‐Hwan,Lee Jong Wook,Lin Chien‐Chin,Lukina Elena,Martynova Elena,Matsumura Itaru,Meike Galina,Menosi Gualandro Sandra Fátima,Minaeva Natalia,Mori Yasuo,Morita Kimio,Morselli Ramalho Fernanda Maria,Mun Yeung‐Chul,Muus Petra,Myasnikov Alexander,Naito Kensuke,Ninomiya Haruhiko,Nogami Ayako,Notaro Rosario,Ojeda Gutierrez Emilio,Okada Masaya,Okamoto Shinichiro,Olkhovik Tatiana,Pane Fabrizio,Paquette Ronald,Park Joon Seong,Peffault de la Tour Régis,Piatek Caroline,Piekarska Agnieszka,Pontes Reis Marcos Laercio,Pospelova Tatiana,Ptushkin Vadim,Roeth Alexander,Rojnuckarin Ponlapat,Rosa Pessoa Viviani de Lourdes,Rossi Blanca,Salleh Sinari,Salvino de Araujo Marco Aurelio,Samuel Desmond,Saraeva Natalya,Schrezenmeier Hubert,Shatokhin Yury,Shelekhova Tatiana,Sohn Sang Kyun,Steinerova Katerina,Sunami Kazutaka,Syed Abdul Kadir Sharifah Shahnaz,Tamura Shinobu,Theunissen Koen,Toh See Guan,Tomita Akihiro,Torregrosa Diaz José Miguel,Ueda Yasutaka,Usuki Kensuke,Vannucchi Alessandro Maria,Viboonjuntra Pongtep,Viigimaa Iige,Volkova Svetlana,Wang Ming‐Chung,Won Jong‐Ho,Wong Lily Lee Lee,Wong Voon Fei,Yap Eng Soo,Yeh Su‐Peng,Yhim Ho‐Young,Yonemura Yuji,Yoon Sung‐Soo,Zhuravkov Andrey,

Affiliation:

1. Department of Haematological Medicine King's College Hospital, National Institute for Health Research and Wellcome King's Clinical Research Facility and King's College London London UK

2. NHS Teaching Hospitals Leeds UK

3. Radboudumc Nijmegen Netherlands

4. NTT Medical Center Tokyo Tokyo Japan

5. RM Gorbacheva Research Institute Pavlov University St Petersburg Russia

6. Alexion, AstraZeneca Rare Disease Boston Massachusetts USA

7. Osaka University Graduate School of Medicine Suita Japan

8. Department of Hematology Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea Seoul Republic of Korea

9. Hôpital Saint‐Louis AP‐HP Paris France

Funder

Alexion Pharmaceuticals

Publisher

Wiley

Subject

Hematology,General Medicine

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