Pharmacokinetics and pharmacodynamics of gamithromycin in pulmonary epithelial lining fluid in naturally occurring bovine respiratory disease in multisource commingled feedlot cattle

Author:

DeDonder K. D.1,Apley M. D.2,Li M.3,Gehring R.3,Harhay D. M.4,Lubbers B. V.5,White B. J.2,Capik S. F.1,KuKanich B.6,Riviere J. E.3,Tessman R. K.7

Affiliation:

1. Diagnostic Medicine/Pathobiology; Kansas State University College of Veterinary Medicine; Manhattan KS USA

2. Clinical Sciences; Kansas State University College of Veterinary Medicine; Manhattan KS USA

3. Institute of Computational Comparative Medicine; Kansas State University College of Veterinary Medicine; Manhattan KS USA

4. USDA ARS US Meat Animal Research Center; Clay Center NE USA

5. Kansas State Veterinary Diagnostic Laboratory; Kansas State University College of Veterinary Medicine; Manhattan KS USA

6. Anatomy and Physiology; Kansas State University College of Veterinary Medicine; Manhattan KS USA

7. Pharmaceutical Research and Development; Merial; Duluth GA USA

Funder

Merial

Duluth

Georgia

Publisher

Wiley

Subject

General Veterinary,Pharmacology

Reference29 articles.

1. Advanced-generation macrolides: tissue-directed antibiotics;Amsden;International Journal of Antimicrobial Agents,2001

2. Clinical and Laboratory Standards Institute VET01-A4 2013 Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals

3. Robust population pharmacokinetic experiment design;Dodds;Journal of Pharmacokinetics and Pharmacodynamics,2005

4. Immunomodulatory effects of tulathromycin on apoptosis, efferocytosis, and proinflammatory leukotriene B4 production in leukocytes from Actinobacillus pleuropneumoniae-or zymosan-challenged pigs;Duquette;American Journal of Veterinary Research,2015

5. Effects of tylosin, tilmicosin and tulathromycin on inflammatory mediators in bronchoalveolar lavage fluid of lipopolysaccharide-induced lung injury;Er;Acta Veterinaria Hungarica,2012

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