ADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta‐analysis

Author:

Karimi Leila1ORCID,Vijverberg Susanne J.234,Engelkes Marjolein1,Hernandez‐Pacheco Natalia56,Farzan Niloufar24,Soares Patricia7ORCID,Pino‐Yanes Maria689ORCID,Jorgensen Andrea L.10,Eng Celeste11,Mukhopadhyay Somnath7,Schieck Maximilian1213,Kabesch Michael12,Burchard Esteban G.1114,Chew Fook Tim15,Sio Yang Yie15,Potočnik Uroš1617,Gorenjak Mario16,Hawcutt Daniel B.1819,Palmer Colin N.20,Turner Steve21ORCID,Janssens Hettie M.22,Maitland‐van der Zee Anke H.234,Verhamme Katia M. C.123,

Affiliation:

1. Department of Medical Informatics Erasmus University Medical Center Rotterdam The Netherlands

2. Department of Respiratory Medicine Amsterdam University Medical CentersUniversity of Amsterdam Amsterdam The Netherlands

3. Department of Pediatric Respiratory Medicine and Allergy Emma Children’s Hospital Amsterdam University Medical CentersUniversity of Amsterdam Amsterdam The Netherlands

4. Division of Pharmacoepidemiology and Clinical Pharmacology Utrecht Institute for Pharmaceutical Sciences (UIPS) Faculty of Science Utrecht University Utrecht The Netherlands

5. Research Unit Hospital Universitario N.S. de Candelaria Universidad de La Laguna Santa Cruz de Tenerife Spain

6. Genomics and Health Group Department of Biochemistry, Microbiology, Cell Biology and Genetics Universidad de La Laguna San Cristóbal de La Laguna Santa Cruz de Tenerife Spain

7. Academic Department of Pediatrics Brighton & Sussex Medical School Royal Alexandra Children's Hospital Brighton UK

8. CIBER de Enfermedades Respiratorias Instituto de Salud Carlos III Madrid Spain

9. Instituto de Tecnologías Biomédicas (ITB) Universidad de La Laguna Santa Cruz de Tenerife Spain

10. Department of Health Data Science Institute of Population Health University of Liverpool Liverpool UK

11. Department of Medicine University of California San Francisco CA USA

12. Department of Pediatric Pneumology and Allergy University Children’s Hospital Regensburg (KUNO Regensburg Germany

13. Department of Human Genetics Hannover Medical School Hannover Germany

14. Department of Bioengineering and Therapeutic Sciences University of California San Francisco CA USA

15. Department of Biological Sciences National University of Singapore Singapore Singapore

16. Center for Human Molecular Genetics and Pharmacogenomics Faculty of Medicine University of Maribor Maribor Slovenia

17. Laboratory for Biochemistry, Molecular Biology and Genomics Faculty of Chemistry and Chemical Engineering University of Maribor Maribor Slovenia

18. Members of Liverpool Health Partners University of Liverpool and Alder Hey Children’s Hospital Liverpool UK

19. NIHR Alder Hey Clinical Research Facility Alder Hey Children's Hospital Liverpool UK

20. Division of Cardiovascular and Diabetes Medicine Ninewells Hospital and Medical School University of Dundee Dundee UK

21. Child Health University of Aberdeen Aberdeen UK

22. Department of Pediatrics/division Respiratory Medicine and Allergology Erasmus MC/Sophia Children's Hospital Erasmus University Medical Center Rotterdam The Netherlands

23. Department of Bioanalysis Ghent University Ghent Belgium

Funder

Chief Scientist Office

National Heart, Lung, and Blood Institute

American Asthma Foundation

National Institute of Environmental Health Sciences

European Commission

Horizon 2020 Framework Programme

GlaxoSmithKline

National Institute for Health Research

Javna Agencija za Raziskovalno Dejavnost RS

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

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