Affiliation:
1. Schweiger Dermatology Group Hackensack New Jersey USA
2. Icahn School of Medicine at Mt. Sinai New York New York USA
3. Radboud UMC Nijmegen Andriessen Consultants Malden The Netherlands
4. Gold Skin Care Center Vanderbilt University School of Nursing Nashville Tennessee USA
5. Department of Dermatology NYU School of Medicine New York New York USA
6. Cosmetic Enhancement Center for Clinical and Cosmetic Research Aventura Florida USA
7. Medical and Cosmetic Dermatology North Bergen New Jersey USA
Abstract
AbstractBackgroundThe demand for nonsurgical facial rejuvenation options is growing, yet the periorbital region remains an area of relative unmet need. This review explores nonsurgical options for facial rejuvenation and the role of oxymetazoline hydrochloride ophthalmic solution, 0.1%, in treating age‐related blepharoptosis as part of periorbital rejuvenation.MethodsAdvisors experienced in facial rejuvenation met to discuss existing literature on the upper face and periorbital rejuvenation and the role of oxymetazoline hydrochloride ophthalmic solution, 0.1%, in treating facial aging.ResultsAn array of nonsurgical options exist to address the signs of aging, including minimally invasive treatments, such as botulinum toxin injections and dermal fillers, and noninvasive therapy, such as lasers, chemical peels, and microdermabrasion. However, treating age‐related ptosis in periorbital rejuvenation is mainly addressed surgically. The newly approved α‐adrenergic receptor agonist oxymetazoline hydrochloride ophthalmic solution, 0.1%, provides a novel non‐interventional approach to blepharoptosis.ConclusionsFacial rejuvenation is highly sought‐after in this post‐pandemic era. Each nonsurgical treatment option has its advantages and drawbacks. A patient‐centered approach is necessary to select the appropriate procedure considering the patient's concerns and aesthetic sensibilities. The eyes are an area of primary concern for patients, yet surgery is the gold standard for treating ptosis. Oxymetazoline hydrochloride ophthalmic solution, 0.1%, is a safe and effective nonsurgical treatment for blepharoptosis.