Age-related changes of proinsulin processing in diabetic and non-diabetic Japanese individuals
Author:
Affiliation:
1. Diabetes Center; Shin-Suma Hospital; Kobe Japan
2. Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine; Toho University Graduate School of Medicine; Tokyo Japan
Publisher
Wiley
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/ggi.13303/fullpdf
Reference21 articles.
1. Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus;Røder;J Clin Endocrinol Metab,1998
2. Estimated proinsulin processing activity of prohormone convertase (PC) 1/3 rather than PC2 is decreased in pancreatic β-cells of type 2 diabetic patients;Ozawa;Endocr J,2014
3. What beta-cell defect could lead to hyperproinsulinemia in NIDDM? Some clues from recent advances made in understanding the proinsulin-processing mechanism;Rhodes;Diabetes,1994
4. A basic study of the intact proinsulin assay reagent;Koyama;JJCLA,2006
5. Prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in U.S. population aged 20-74 yr;Harris;Diabetes,1987
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