Proteostasis disturbances and endoplasmic reticulum stress contribute to polycystic liver disease: New therapeutic targets

Author:

Santos‐Laso Alvaro1,Izquierdo‐Sanchez Laura12,Rodrigues Pedro M.1,Huang Bing Q.3,Azkargorta Mikel24,Lapitz Ainhoa1,Munoz‐Garrido Patricia1,Arbelaiz Ander1,Caballero-Camino Francisco J.15,Fernández‐Barrena Maite G.26,Jimenez‐Agüero Raul1,Argemi Josepmaria6,Aragon Tomas6,Elortza Felix24,Marzioni Marco7ORCID,Drenth Joost P. H.8,LaRusso Nicholas F.3,Bujanda Luis12,Perugorria Maria J.129,Banales Jesus M.129ORCID

Affiliation:

1. Department of Liver and Gastrointestinal Diseases Biodonostia Research Institute – Donostia University HospitalUniversity of the Basque Country (UPV/EHU) San Sebastian Spain

2. National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehdInstituto de Salud Carlos III) Madrid Spain

3. Division of Gastroenterology and Hepatology Mayo Clinic Rochester MN USA

4. Proteomics Platform CIC bioGUNEProteoRed‐ISCIIIBizkaia Science and Technology Park Derio Spain

5. Department of Organic Chemistry I Center for Innovation in Advanced Chemistry (ORFEO‐CINQA) University of the Basque Country (UPV/EHU) San Sebastian Spain

6. Division of Hepatology CIMA‐University of Navarra Pamplona Spain

7. Department of Gastroenterology and Hepatology Università Politecnica delle Marche Ancona Italy

8. Department of Gastroenterology and Hepatology Radboud University Medical Center Nijmegen The Netherlands

9. IKERBASQUEBasque Foundation for Science Bilbao Spain

Funder

European Molecular Biology Organization

Eusko Jaurlaritza

Instituto de Salud Carlos III

European Regional Development Fund

Publisher

Wiley

Subject

Hepatology

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