A Randomized Trial Comparing the Pharmacokinetics, Safety, and Tolerability of DFN-02, an Intranasal Sumatriptan Spray Containing a Permeation Enhancer, With Intranasal and Subcutaneous Sumatriptan in Healthy Adults

Author:

Munjal Sagar1,Gautam Anirudh1,Offman Elliot2,Brand-Schieber Elimor1,Allenby Kent1,Fisher Dennis M.3

Affiliation:

1. Dr. Reddy's Laboratories Ltd; Princeton NJ USA

2. Dr. Reddy's Laboratories, Hyderabad, India (A. Gautam); Celerion; Montreal Canada

3. P Less Than; San Francisco CA USA

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Reference32 articles.

1. Practice parameter: Evidence-based guidelines for migraine headache (an evidence-based review);Silberstein;Neurology.,2000

2. Safety, tolerability, and pharmacokinetics of sumatriptan in healthy subjects following ascending single intranasal doses and multiple intranasal doses;Moore;Cephalalgia.,1997

3. GlaxoSmithKline https://gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Imitrex_Injection/pdf/IMITREX-INJECTION-PI-PPI-PIL-COMBINED.PDF 2015

4. GlaxoSmithKline https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Imitrex_Tablets/pdf/IMITREX-TABLETS-PI-PIL.PDF 2015

5. GlaxoSmithKline https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Imitrex_Nasal_Spray/pdf/IMITREX-NASAL-SPRAY-PI-PIL.PDF 2015

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