IL-13-producing BLT1-positive CD8 cells are increased in asthma and are associated with airway obstruction

Author:

Dakhama A.1,Collins M. L.1,Ohnishi H.1,Goleva E.1,Leung D. Y. M.1,Alam R.2,Sutherland E. R.2,Martin R. J.2,Gelfand E. W.1

Affiliation:

1. Department of Pediatrics; National Jewish Health; Denver; CO; USA

2. Department of Medicine; National Jewish Health; Denver; CO; USA

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference35 articles.

1. Asthma;Busse;N Engl J Med,2001

2. The role of T lymphocytes in the pathogenesis of asthma;Larche;J Allergy Clin Immunol,2003

3. Heterogeneity of CD4(+) and CD8(+) T cells;Woodland;Curr Opin Immunol,2003

4. Expression of IL-4 and IL-5 mRNA and protein product by CD4 +  and CD8 +  T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics;Ying;J Immunol,1997

5. Bronchial CD8 cell infiltrate and lung function decline in asthma;Rensen;Am J Respir Crit Care Med,2005

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