Alteration of the immune environment in bone marrow from children with recurrent B cell precursor acute lymphoblastic leukemia

Author:

Mikami Takashi1ORCID,Kato Itaru1ORCID,Wing James Badger2,Ueno Hiroo1,Tasaka Keiji1ORCID,Tanaka Kuniaki1,Kubota Hirohito1,Saida Satoshi1,Umeda Katsutsugu1ORCID,Hiramatsu Hidefumi1,Isobe Tomoya3,Hiwatari Mitsuteru3,Okada Ai4,Chiba Kenichi4,Shiraishi Yuichi4,Tanaka Hiroko5,Miyano Satoru5,Arakawa Yuki6,Oshima Koichi6,Koh Katsuyoshi6,Adachi Souichi7,Iwaisako Keiko8,Ogawa Seishi91011,Sakaguchi Shimon12,Takita Junko1

Affiliation:

1. Department of Pediatrics Graduate School of Medicine Kyoto University Kyoto Japan

2. Laboratory of Human Immunology Immunology Frontier Research Center Osaka University Osaka Japan

3. Department of Pediatrics Graduate School of Medicine The University of Tokyo Tokyo Japan

4. Division of Genome Analysis Platform Development National Cancer Center Research Institute Tokyo Japan

5. M&D Data Science Center Tokyo Medical and Dental University Tokyo Japan

6. Department of Hematology/Oncology Saitama Children’s Medical Center Saitama Japan

7. Department of Human Health Sciences Graduate School of Medicine Kyoto University Kyoto Japan

8. Department of Medical Life Systems Faculty of Life and Medical Sciences Doshisha University Kyoto Japan

9. Department of Pathology and Tumor Biology Graduate School of Medicine Kyoto University Kyoto Japan

10. Department of Molecular Oncology Institute for the Advanced Study of Human Biology (WPI‐ASHBi) Kyoto Japan

11. Department of Medicine Center for Hematology and Regenerative Medicine Karolinska Institute Stockholm Sweden

12. Laboratory of Experimental Immunology Immunology Frontier Research Center Osaka University Osaka Japan

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Reference55 articles.

1. Acute lymphoblastic leukaemia

2. Treatment of Relapsed Precursor-B Acute Lymphoblastic Leukemia With Intensive Chemotherapy

3. Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia

4. Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia

5. A randomized phase 3 trial of Blinatumomab Vs. chemotherapy as post‐reinduction therapy in high and intermediate risk (HR/IR) first relapse of B‐acute lymphoblastic leukemia (B‐ALL) in children and adolescents/young adults (AYAs) demonstrates superior efficacy and tolerability of Blinatumomab: A report from children's oncology group study AALL1331;Patrick AB;Blood,2019

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