Feline leukocyte adhesion (CD18) deficiency caused by a deletion in the integrin β2 (ITGB2 ) gene

Author:

Bauer Thomas R.1ORCID,Pratt Suzanne M.2ORCID,Palena Christina M.3,Raj Karthik4,Giger Urs4ORCID

Affiliation:

1. Experimental Transplantation and Immunology Branch; National Cancer Institute; National Institutes of Health; Department of Health and Human Services; Bethesda MD USA

2. Antech Diagnostics; Portland OR USA

3. Mountain View Veterinary Hospital; Vancouver WA USA

4. Section of Medical Genetics; School of Veterinary Medicine; University of Pennsylvania; Philadelphia PA USA

Funder

National Cancer Institute

National Institutes of Health

Publisher

Wiley

Subject

General Veterinary

Reference38 articles.

1. Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins;Anderson;Annu Rev Med,1987

2. Molecular definition of the bovine granulocytopathy syndrome: identification of deficiency of the Mac-1 (CD11b/CD18) glycoprotein;Kehrli;Am J Vet Res,1990

3. Canine leucocyte adhesion deficiency in Irish red and white setters;Debenham;J Small Anim Pract,2002

4. Canine leukocyte adhesion deficiency: presence of the Cys36Ser β-2 integrin mutation in an affected US Irish setter cross-breed dog and in US Irish Red and White setters;Foureman;J Vet Intern Med,2002

5. Deficiency of leukocyte surface glycoproteins Mo1, LFA-1, and Leu M5 in a dog with recurrent bacterial infections: an animal model;Giger;Blood,1987

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