The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7,in vitro

Author:

Gloeckner Christian Johannes,Schumacher Annette,Boldt Karsten,Ueffing Marius

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference42 articles.

1. Zeroing in on LRRK2-linked pathogenic mechanisms in Parkinson’s disease. Biochim;Biskup;Biophys. Acta,2008

2. Dynamic and redundant regulation of LRRK2 and LRRK1 expression;Biskup;BMC Neurosci.,2007

3. JNK signalling: a possible target to prevent neurodegeneration;Borsello;Curr. Pharm. Des.,2007

4. Roc, a Ras/GTPase domain in complex proteins;Bosgraaf;Biochim. Biophys. Acta,2003

5. Genetics of Parkinson’s disease: LRRK2 on the rise;Brice;Brain,2005

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