Abstract
Hepatitis E virus (HEV) is the most common cause of AVH in developing countries. HEV causes a self-limiting infection that is transmitted mainly through the consumption of contaminated food and water. Our study aimed to find out the seroprevalence of HEV infection. Detected both IgG & IgM antibodies from 100 asymptomatic antenatal women. ELISA (DIA PRO, Italy) was used to detect antibodies. Seropositivity was found in 9% of pregnant women, all might have been exposed to HEV infection previously. It could be unnoticed due to its self-limiting nature. IgG was 5% and IgM was 6%. Both IgM & IgG were detected in two pregnant women. Untreated water was used by the majority of women irrespective of their educational status. Though it is a self-limiting disease, it is necessary to screen for its antibody. Awareness about the modes of transmission & complications needs to be addressed in the community. It is necessary to do further studies for screening for HEV infection as there is a very limited number of studies published from South India.
Publisher
Journal of Pure and Applied Microbiology
Subject
Applied Microbiology and Biotechnology,Microbiology,Biotechnology
Reference21 articles.
1. 1. Gupta E, Agarwala P. Hepatitis E virus infection: An old virus with a new story. Indian J Med Microbiol. 2018;36(3):317. doi: 10.4103/ijmm.IJMM_18_149
2. 2. Van der Poel WH. Food and environmental routes of Hepatitis E virus transmission. Curr Opin Virol. 2014;4:91-96. doi: 10.1016/j.coviro.2014.01.006
3. 3. Naik SR, Aggarwal R, Salunke PN, Mehrotra NN. A large waterborne viral hepatitis E epidemic in Kanpur, India. Bull World Health Organ. 1992;70(5):597-604. PMCID: PMC2393368.
4. 4. Di Profio F, Melegari I, Palombieri A, et al. High prevalence of hepatitis E virus in raw sewage in Southern Italy. Virus Res. 2019;272:197710. doi: 10.1016/j.virusres.2019.197710
5. 5. Tripathy AS, Puranik S, Sharma M, Chakraborty S, Devakate UR. Hepatitis E virus seroprevalence among blood donors in Pune, India. J Med Virol. 2019;91(5):813-819. doi: 10.1002/jmv.25370