About molecular transformations of biopolymers

Abstract

Almost no attention is paid to molecular processes in the body in the human sciences, the efficiency of metabolism, temperature, fatigue and relaxation, stretching and rupture of tissue cells, their healing, symptoms of diseases, etc. are discussed. about a human. This is due to insufficient training of physicians, biologists, epidemiologists, and gerontologists in the field of physical chemistry of polymers, although they are interested in a biopolymer object - a person. The basis of his body is proteins (polypeptides) and polynucleotides, DNA, their genes and turns. The paper deals with changes in biopolymers during physical and mental stress, in disease and treatment. The main forms of proteins and polynucleotides, the effect of the pH of the medium, its changes with temperature, on their sterioisometry, macromolecular structure and properties are described. The initial basis for the presented physicochemical analysis was the processes occurring during loading of muscle tissues. The transformation of proteins, DNA and genes is based on the alkalization of biopolymers with acetylcholine, which is released during muscle contraction, followed by neutralization of its action with cholinesterase to stop movement. With regular physical (and mental) overloads, genetic transformations occur and a so-called "genetic" fatigue appears (the cell genome changes). The recovery of biopolymers is carried out by lactic acid, which is formed when muscles are loaded in excess and has a prolonged effect on macromolecules. The concept of molecular transformations of biopolymers has been applied to describe human diseases and treatment, including heart attack and COVID-19. The proposed spiritual, carbon dioxide restorative actions, combined with active mental work and increased stress, can increase immunity, reduce morbidity (infection with microbes, and in the case of SARS-CoV 2, prevent the appearance of ATE 2 "traitor proteins"), as well as delay old age.