Affiliation:
1. All-Russian Scientific Research Institute of Tobacco, Makhorka and Tobacco Products
Abstract
Investigation of some toxic compounds concentrations in aerosol of new class of tobacco products - tobacco heating systems and comparing their levels with regular cigarettes aerosol is an important step in understanding whether these products are low-risk, as some manufacturers claim. Three popular in Russia cigarette brands, reference cigarette 3R4F and new heated tobacco products (HTP) were tested for levels of emissions of some harmful and potentially harmful constituents (HPHC). Aerosols of these products were collected under the ISO intense smoking regime and quantified for levels of N'-nitrosonornicotine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, acrolein, acetaldehyde, formaldehyde. Levels of above mentioned HPHCs were measured by the high-performance liquid chromatography / mass spectrometry (HPLC/MS-MS). The results demonstrate that highest levels of measured HPHCs are obtained for reference cigarette 3R4F. As for popular in Russia cigarette brands their levels vary greatly and for some compounds can be very close to levels of 3R4F aerosol. Levels of all measured HPHCs in aerosol of HTP were significantly lower compared to all cigarettes. This can be explained by specific mechanism of HTPs aerosol formation without pyrolytic and pyrosynthetic reactions which are typical to all combustive tobacco products due to their high temperature of the process.
Publisher
FSBEI HE Voronezh State University of Engineering Technologies
Subject
General Agricultural and Biological Sciences
Reference21 articles.
1. 1 US Department of Health and Human Services et al. Reducing tobacco use: a report of the Surgeon General. 2000.
2. 2 Shapiro H. No fire, no smoke: the global state of tobacco harm reduction 2018. London: Knowledge-Action // Change. 2018. Available at: https://gsthr.org/report/full-report
3. 3 McNeill A., Brose L.S., Calder R. et al. E-cigarettes: an evidence update. A report commissioned by Public Health England // Public Health England. 2015. V. 111. P. 14-15. Available at: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/733022
4. 4 Simonavicius E., McNeill A., Shahab L. et al. Heat-not-burn tobacco products: a systematic literature review // Tobacco control. 2019. V. 28. №. 5. P. 582-594. doi: 10.1136/tobaccocontrol 2018–054419
5. 5 Farsalinos K.E., Le Houezec J. Regulation in the face of uncertainty: the evidence on electronic nicotine de-livery systems (e-cigarettes) // Risk Manag Health Policy. 2015. V. 8. P. 157–167. doi:10.2147/RMHP.S62116
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