Soluble esterases of human lung

Abstract

The soluble esterases of human lung compared to liver and serum have been illustrated on starch gel. A common zone of esterases appears to exist in nearly all human tissues and may be physiologically important acetylesterases. The most marked difference between lung and liver esterases exists in the ones moving farthest towards the anode at pH 7.0. Lactic and malic dehydrogenase patterns in the two tissues are also quite different. The zone 2 esterases appear to have a molecular weight of approximately 150 000 and those of zones 1 and 3 may be in the range of 50 000 as shown by G-200 Sephadex column chromatography.