Author:
Cheema-Dhadli Surinder,Halperin Mitchell L.
Abstract
The Michaelis constant (Km) for citrate for the hepatic mitochondrial citrate transporter of fed rats is 239 μM. This Km increases approximately twofold in mitochondria of fasted or diabetic rats. The long-chain fatty acyl-CoA content was approximately twofold higher in mitochondria from fasted and diabetic rats and could account for this increased Km. The role of regulation of the mitochondrial citrate transporter in lipogenesis is discussed.
Publisher
Canadian Science Publishing
Cited by
28 articles.
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