Affiliation:
1. Department of Chemistry and FQRNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke St. W., Montreal, QC H3A 0B8, Canada.
Abstract
Carbon–carbon bond formation is the core of organic synthesis, in which organometallic reagents play the key role in the forms of 1,2-nucleophilic additions, conjugate additions, and transition-metal catalyzed cross-couplings. These reactions have enabled the production of a wide range of organic molecules in our society. Despite the enormous power of organometallic reagents in chemical synthesis, they have inherent drawbacks in the eyes of future sustainability. This account summarizes our efforts over the past three decades on the exploration of new scientific means to overcome the drawbacks and limitations of these classical organometallic reactions.
Publisher
Canadian Science Publishing
Subject
Organic Chemistry,General Chemistry,Catalysis
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