Increased Diamine Oxidase Activity in the Intestinal Lymph of Rats on Fat Ingestion

Abstract

When diamine oxidase activity was measured in the intestinal lymph of rats, a marked increase in the enzyme activity was observed shortly after oral administration of olive oil. The response was similar to that seen after intraperitoneal injection of heparin. Substitution of glucose solution for olive oil did not produce this response. Administration of olive oil on successive days resulted in a successively greater increase in diamine oxidase activity. Combined administration of olive oil and intraperitoneal injection of heparin gave diamine oxidase activity levels whch were greater than the sum of the increases resulting from the separate treatments.