Hydrolysis of α-bromoisobutyrate ion in water

Abstract

The temperature dependence of the rate of hydrolysis of α-bromoisobutyrate ion in water was determined over a temperature range 9–37 °C. From these data corresponding values of ΔH≠, ΔS≠, and ΔCP≠ have been derived. The implication of these terms, together with corresponding data for hydrolysis in D2O and for the secondary deuterium isotope effect from the hydrolysis of (CD3)2CBrCOO−, provide a basis for reexamining the detailed mechanism with particular reference to accompanying solvent reorganization.