AROMATIC SUBSTITUTION: PART II. THE REACTION OF VARIOUS 3-SUBSTITUTED PYRIDINE DERIVATIVES AND OF QUINOLINE WITH PHENYLLITHIUM

Author:

Abramovitch R. A.,Ahmed K. S.,Giam Choo-Seng

Abstract

Phenyllithium and pyridine-3-N,N -diethylsulphonamide gave the expected 2-phenyl derivative exclusively. Contrary to a previous report some 2,3-diphenylpyridine is formed with 3-phenylpyridine. No pyridyne intermediate seems to be formed in the reaction of phenyllithium with 3-bromopyridine. The reactions of phenyllithium with quinoline and with N-benzylpyridinium chloride have also been studied and are discussed.

Publisher

Canadian Science Publishing

Subject

Organic Chemistry,General Chemistry,Catalysis

Cited by 29 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Vibrational spectroscopic, 1H NMR and quantum chemical computational study of 4-hydroxy-2-oxo-1,2-dihydroquinoline-8-carboxylic acid;Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy;2014-03

2. Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition toN-Activated Pyridines;Chemical Reviews;2012-02-21

3. Alkylquinolines and Arylquinolines;Chemistry of Heterocyclic Compounds: A Series Of Monographs;2008-01-02

4. Organometallic Compounds of Pyridine;Chemistry of Heterocyclic Compounds: A Series Of Monographs;2008-01-02

5. Halopyridines;Chemistry of Heterocyclic Compounds: A Series Of Monographs;2008-01-02

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