Author:
Seemann C. von,Lucas C. C.
Abstract
A method is described for the synthesis of (1-acetylaminobenzene-4-sulphonamido)-2-thiophene and of (1-aminobenzene-4-sulphonamido)-2-thiophene, also called 2-sulphanilamido-thiophene. The acute toxicity of the above compounds has been determined and an evaluation made of their chemotherapeutic activity in experimental infections of white mice with Pneumococcus Type I; 2-sulphanilamido-thiophene shows no chemotherapeutic activity.
Publisher
Canadian Science Publishing
Subject
Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Aminothiophenes and their Derivatives;Chemistry of Heterocyclic Compounds: A Series Of Monographs;2008-01-02
2. Biological and Pharmacological Activity of Thiophene and its Derivatives;Chemistry of Heterocyclic Compounds: A Series Of Monographs;2008-01-02
3. The Nitro- and Aminothiophenes;Chemistry of Heterocyclic Compounds: A Series Of Monographs;2008-01-02
4. 2-Aminothiophene. Heterocyclization of benzylthionitriles;Journal of Heterocyclic Chemistry;1969-04
5. 2-Aminothiophene. Heterocyclization of benzylthionitriles;Tetrahedron Letters;1967-01