The effect of stereochemistry on 1JC—H at the sp2 carbons of oxime, hydrazone, and imine derivatives of aldehydes

Abstract

A comparison of the magnitudes of 1JC—H at the aldehydic carbon of both the syn and anti isomers of aldehyde derivatives (oximes, hydrazones, and imines) has shown a consistently greater value, by about 20 Hz, for the syn isomer. Regardless of its origin, this stereochemical correlation should prove useful in providing configurational assignments.