THE DIFFERENTIAL DETERMINATION OF CATECHOLAMINES IN URINE

Author:

Drujan B. D.,Sourkes T. L.,Layne D. S.,Murphy G. F.

Abstract

Details of uniform procedures for the routine determination of adrenaline, noradrenaline, and dopamine in urine are given. The first two compounds are determined by a trihydroxyindole method; for dopamine, a modification of the method of Carlsson and Waldeck is used. Determination of adrenaline and noradrenaline is illustrated using three different types of fluorometer. Normal values for the 24-hour excretion of these compounds in the urine of normal adults are in micrograms: adrenaline, 16.4 μg ± 1.1, noradrenaline, 54.9 μg ± 3.2, dopamine, 198.8 μg ± 36.2 (mean ± standard error). Some examples of the levels of catecholamine excretion in various clinical states are given.

Publisher

Canadian Science Publishing

Subject

General Medicine

Reference10 articles.

Cited by 50 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Levodopa and dopamine agonists in the treatment of Parkinson's disease;Discoveries in Pharmacology;2023

2. Maturation of the Sympatho-Adrenal System and Clinical Values of the Determination of Urinary Catecholamine Excretion;Asia-Oceania Journal of Obstetrics and Gynaecology;2010-05-24

3. Urinary excretion of catecholamines in hospitalized and non-hospitalized healthy children and adolescents;Scandinavian Journal of Clinical and Laboratory Investigation;1998-01

4. Norepinephrine in the Affective Disorders: Classic Biochemical Approaches;The Catecholamines in Psychiatric and Neurologic Disorders;1985

5. Chapter 4 Fluorescence Techniques for Detection and Quantitation of Amines;Techniques and Instrumentation in Analytical Chemistry;1982

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