Gene content and organization of a 281-kbp contig from the genome of the extremely thermophilic archaeon,Sulfolobus solfataricusP2

Author:

Charlebois Robert L,Singh Rama K,Chan-Weiher Christina C.-Y,Allard Ghislaine,Chow Cynthia,Confalonieri Fabrice,Curtis Bruce,Duguet Michel,Erauso Gael,Faguy David,Gaasterland Terry,Garrett Roger A,Gordon Paul,Jeffries Alex C,Kozera Catherine,Kushwaha Neena,Lafleur Édith,Medina Nadine,Peng Xu,Penny Susanne L,She Qunxin,St. Jean Andrew,van der Oost John,Young Felix,Zivanovic Yvan,Doolittle W Ford,Ragan Mark A,Sensen Christoph W

Abstract

The sequence of a 281-kbp contig from the crenarchaeote Sulfolobus solfataricus P2 was determined and analysed. Notable features in this region include 29 ribosomal protein genes, 12 tRNA genes (four of which contain archaeal-type introns), operons encoding enzymes of histidine biosynthesis, pyrimidine biosynthesis, and arginine biosynthesis, an ATPase operon, numerous genes for enzymes of lipopolysaccharide biosynthesis, and six insertion sequences. The content and organization of this contig are compared with sequences from crenarchaeotes, euryarchaeotes, bacteria, and eukaryotes. Key words: Archaea, Sulfolobus Genome Project, comparative genomics, bioinformatics.

Publisher

Canadian Science Publishing

Subject

Genetics,Molecular Biology,General Medicine,Biotechnology

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