Studies on complex compounds. V. Coordination compounds of mercury and biologically active amines

Abstract

Five mercury complexes were synthesized by condensation of mercuric chloride with different biologically active amines. In the present study D-amphetamine, L-amphetamine, DL-amphetamine, methyl-amphetamine, ephedrine, and tyramine were used where a stereoisomeric effect was observed during the formation of the mercury complexes. The complex compound synthesized from DL-amphetamine was found to be a mixture of the mercury complexes of D-amphetamine and L-amphetamine, and the difference in their solubilities was utilized for their separation. The estimation of the carbon, hydrogen, and nitrogen content, the determination of the amount of chlorine and mercury, and measurements of the infrared absorption spectra at 700–3500 cm−1 indicated the ratio of 2:1 for amine to mercury in these coordination compounds. Further characterization of these mercury complexes was done by ultraviolet absorption spectra and conductance measurements.