Alcoxy-2, aryloxy-2, acyloxy-2 cyclohexanones. Synthèse et étude de leur équilibre conformationnel

Abstract

We show a linear Hammett correlation in the conformational equilibrium of 2-aryloxycyclohexanones when the X substituent located para on the phenyl ring is electron withdrawing. This leads to the prediction of the equatorial position of the substituent in the 2-acyloxycyclohexanones. The conformational equilibria of 2-alcoxycyclohexanones (R = CH3 to C(CH3)3) also are examined.