Amine and thiazole substituted γ-butyrolactones from naturally occurring limonene-Reference-Cited by-同舟云学术

Amine and thiazole substituted γ-butyrolactones from naturally occurring limonene

Published:2011-06 Issue:6 Volume:89 Page:639-644
ISSN:0008-4042
Container-title:Canadian Journal of Chemistry
language:en
Short-container-title:Can. J. Chem.

Author:

Kaur Pushpinder¹,Das Pralay¹,Chaudhary Abha¹,Singh Bikram¹

Affiliation:

1. Natural Plant Products Division, Institute of Himalayan Bioresource Technology, Palampur (H.P.) 176061, India.

Abstract

Substituted γ-butyrolactones are important structural motifs in several natural products and pharmaceuticals. In this paper, we report the synthesis of novel γ-butyrolactone amine and thiazole derivatives from naturally occurring limonene. Regioselective bromination followed by nucleophilic substitution with different amines and thiourea gave desired products in moderate yield.

Publisher

Canadian Science Publishing

Subject

Organic Chemistry,General Chemistry,Catalysis

Link

http://www.nrcresearchpress.com/doi/pdf/10.1139/v11-016

Reference21 articles.

1. New Entry to Diastereoselective Synthesis of b,g-Disubstituted g-Lactones. Application to "Self-immolative" Enantioselective Synthesis of 5-Alkylbutenolides

2. A novel stereoselective route to γ-butyrolactones

3. Total synthesis of naturally occurring acetogenins: solamin and reticulatacin

4. Stereoselective synthesis of (±)-threo-γ-hydroxy-β-lysine lactone

5. Chemical Studies on Tuberactinomycin. IV. The Chemical Structure of γ-Hydroxy-β-lysine, A New Amino Acid Isolated from Tuberactinomycin A and N

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