Cyclodehydration of certain β-hydroxyketones to substituted aromatic hydrocarbons

Author:

Canonne P.,Holm P.,Leitch L. C.

Abstract

A series of β-hydroxyketones, CH3CR(OH)CH2COCH3, has been converted into substituted aromatic hydrocarbons in 80–90% yields by a double dehydration with cyclization in the presence of acids. The nuclear magnetic resonance spectra of the compounds, several of which are new, have been measured.

Publisher

Canadian Science Publishing

Subject

Organic Chemistry,General Chemistry,Catalysis

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4. A Novel Synthetic Route to 1,3-Disubstituted Naphthalenes;Synthetic Communications;1994-01

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