Effect of various inhibitors on sporulation of Bacillus subtilis crs mutants
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Published:1984-11-01
Issue:11
Volume:30
Page:1337-1343
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ISSN:0008-4166
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Container-title:Canadian Journal of Microbiology
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language:en
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Short-container-title:Can. J. Microbiol.
Author:
Takahashi I.,Sun Dongxu
Abstract
The effect of aliphatic alcohols, cerulenin, and NaCl on sporulation of various catabolite-resistant (crs) mutants of Bacillus subtilis was studied. Mutants carrying crsA or crsF mutations were able to sporulate in the presence of these agents. Other crs mutants were resistant to at least one of the inhibitors. Electron microscopic examination revealed that cerulenin blocks sporulation at stage 0 in wild-type cells, suggesting that early sporulation functions are affected by this antibiotic. The results obtained so far suggest that the functions altered in the crs mutants may be related to the membrane.
Publisher
Canadian Science Publishing
Subject
Genetics,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Immunology,Microbiology
Cited by
2 articles.
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1. Bacillus Subtilis Sigma Factors;Biotechnology & Biotechnological Equipment;1991-01
2. Suppressor mutations for crs mutants of Bacillus subtilis;Canadian Journal of Microbiology;1985-05-01