Phosphate absorption inAplysiacalifornicagut: glucocorticoid inhibition

Abstract

Apical membranes of Aplysia californica foregut epithelia contain a sodium–phosphate symporter. Dexamethasone inhibited the absorptive activity of the sodium–phosphate symporter, whereas amiloride had no effect on the sodium–phosphate symporter. It appears that glucocorticoids or their molluscan equivalent play a role in the overall regulation of phosphate homeostasis by the Aplysia californica gut.Key words: phosphate absorption, sodium–phosphate symporter, glucocorticoid inhibition.