IONIZATION OF ORGANIC COMPOUNDS: II. THIOACETAMIDE IN AQUEOUS SODIUM HYDROXIDE. THE H−ACIDITY FUNCTION

Abstract

The ionization ratio of thioacetamide in aqueous sodium hydroxide, determined spectrophotometrically, is proportional to the concentration of hydroxide ion up to a concentration of about 1 M, and indicates a pKHAof 13.4. For more concentrated solutions the ionizing power increases more rapidly than the hydroxide ion concentration; from the experimentally determined ionization ratios the values of the h−acidity function for 1–6 M sodium hydroxide have been calculated. The relation of h−values to the salting-out parameters and water activities of concentrated sodium hydroxide solutions is discussed.