Intramolecular cyclization reaction — Palladium(0)-catalyzed cyclization is more effective than tin hydride mediated reaction-Reference-Cited by-同舟云学术

Intramolecular cyclization reaction — Palladium(0)-catalyzed cyclization is more effective than tin hydride mediated reaction

Published:2008-04-01 Issue:4 Volume:86 Page:325-332
ISSN:0008-4042
Container-title:Canadian Journal of Chemistry
language:en
Short-container-title:Can. J. Chem.

Author:

Majumdar Krishna C,Debnath Pradip,Taher Abu,Pal Amarta K

Abstract

Intramolecular CH arylation of pyrone, pyridone, uracil, imidazole, and benzimidazole derivatives are carried out in the presence of a Pd catalyst to form potentially bioactive fused heterocyclic compounds, whereas the n-Bu3SnH-mediated aryl radical cyclization of the precursors 3 afforded mainly halogen-reduced uncyclized products.Key words: Pd(0) catalyst, CH arylation, intramolecular cyclization, regioselectivity.

Publisher

Canadian Science Publishing

Subject

Organic Chemistry,General Chemistry,Catalysis

Link

http://www.nrcresearchpress.com/doi/pdf/10.1139/v08-023

Reference20 articles.

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