Author:
Fong C. N.,Atwood H. L.,Jeejeebhoy K. N.,Charlton M. P.
Abstract
The effects of malnutrition on intracellular K+ activity, (aK)i, and membrane potential, Em, were measured by means of double-barrelled K+ -selective microlectrodes in the soleus and gastrocnemius muscles of the rat. (aK)i and Em were measured in vivo in normal anaesthetized animals and in rats subjected to one of two diet restrictions: a 2-day fast or a long-term hypocaloric diet. In the soleus muscle, (aK)i fell by similar amounts in both 2-day fasted and long-term hypocalorically fed rats, while Em depolarized significantly only in hypocalorically fed rats. In the gastrocnemius muscle, neither the 2-day fast nor the hypocaloric diet affected (aK)i or Em. It is suggested that the selective loss of K+ from the soleus muscle may be related to its activity pattern.
Publisher
Canadian Science Publishing
Subject
Physiology (medical),Pharmacology,General Medicine,Physiology
Cited by
10 articles.
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