A novel limonoid from the seeds of Chisocheton siamensis

Abstract

Analysis of an acetone/hexane (1:1) extract of the seeds of Chisocheton siamensis led to the isolation of a novel limonoid, chisosiamensin (1), along with five known limonoids, dysobinin (2), azadiradione (3), mohinin (4), epoxyazadiradione (5), and 6α-acetoxyepoxyazadiradione (6). Their structures were characterized by spectroscopic methods, including UV, IR, NMR, and MS. All isolated limonoids were reported for the first time as secondary metabolites of C. siamensis.Key words: Chisocheton siamensis, Meliaceae, chisosiamensin, limonoids.