Nuclear import of spliceosomal snRNPsThis paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell.-Reference-Cited by-同舟云学术

Nuclear import of spliceosomal snRNPsThis paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell.

Published:2006-03 Issue:3-4 Volume:84 Page:367-376
ISSN:0008-4212
Container-title:Canadian Journal of Physiology and Pharmacology
language:en
Short-container-title:Can. J. Physiol. Pharmacol.

Author:

Rollenhagen Christiane¹,Panté Nelly¹

Affiliation:

1. Department of Zoology, University of British Columbia, 6270 University Boulevard, Vancouver, BC V6T 1Z4, Canada.

Abstract

Uridine-rich small nuclear ribonucleoproteins (U snRNPs) are the building units of the spliceosome. These RNA and protein complexes assemble in the cytoplasm. After proper assembly and RNA maturation, mature U snRNPs are imported into the cell nucleus, where they take part in the splicing process. In this paper we review the current knowledge of how U snRNPs enter the nucleus.

Publisher

Canadian Science Publishing

Subject

Physiology (medical),Pharmacology,General Medicine,Physiology

Link

http://www.nrcresearchpress.com/doi/pdf/10.1139/y05-101

Reference35 articles.

1. Structure of importin-β bound to the IBB domain of importin-α

2. A polypeptide domain that specifies migration of nucleoplasmin into the nucleus

3. An Essential Signaling Role for the m 3 G Cap in the Transport of U1 snRNP to the Nucleus

4. Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport.

5. The Nuclear Transport Factor Karyopherin β Binds Stoichiometrically to Ran-GTP and Inhibits the Ran GTPase Activating Protein

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