Abstract
The general characteristics of acetylcholinesterase are described. The mechanism of action of the enzyme is considered primarily in relation to the two steps in the hydrolysis of acetylcholine, the acetylation and deacetylation reactions. Competitive and non-competitive inhibition, and inhibitions by hydrogen ion and by substrate, are explained in terms of this two-step process. On the basis of the available evidence, a suggestion is made regarding the configuration of groups in the active center.
Publisher
Canadian Science Publishing
Cited by
40 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献