Affiliation:
1. Research Laboratories, Frank W. Horner Limited, Montreal, Que.
Abstract
The acetylation of sulphanilamide by pigeon liver extracts was found to be markedly inhibited by amides of salicylic, 5-bromosalicylic, 5-methylsalicylic, and 6-aminonicotinic acids, and by hydrazides of benzoic, salicylic, 4-aminosalicylic, nicotinic, and isonicotinic acids, as well as by p-aminosalicylic acid. The inhibition by salicylamide and isonicotinylhydrazide (isoniazid) was shown to be competitive in nature.
Publisher
Canadian Science Publishing
Cited by
6 articles.
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