Author:
Hamann H. C.,Spaziano V. T.,Chou T. C.,Price C. C.,Lin H. H.
Abstract
Several 9-furfuryl-6-substituted purines were synthesized by reacting 9-furfuryl-6-chloropurine (5) with the corresponding nucleophilic reagent. The mother compound (5) was prepared by direct cyclization of 4-furfurylamino-5-amino-6-chloropyrimidine (4) with a mixture of ethyl orthoformate and acetic anhydride. The diaminopyrimidine (5) was prepared by treatment of 4,6-dichloro-5-aminopyrimidine with furfurylamine in boiling water.
Publisher
Canadian Science Publishing
Subject
Organic Chemistry,General Chemistry,Catalysis
Cited by
8 articles.
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